BEST SELLER
Big Brain Probiotics®
Big Brain Probiotics®
Vaginal Probiotic
Clinically proven women's probiotic formula that promotes fresh odor, vaginal health, and urinary tract health.†
"Best for Body Balance" - Harper's Bazaar
"2023 Wellness Brand of the Year" - WWD's The Beauty Inc. Awards
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Product Benefits
Product Benefits
- Our clinically proven vaginal probiotic includes nine strains of good bacteria to support the vaginal microbiome, including clinically-studied DE111® to ensure effective delivery through the digestive system. All delivered in one small, vegan capsule.†
- OB/GYN-developed daily probiotics support balanced vaginal pH, a healthy vaginal environment, and urinary tract health.*
- Supports healthy levels of vaginal bacteria and yeast through the gut-vagina microbiome connection.*
- Promotes fresh vaginal odor.*
- Maintains urinary tract health.*
- Capsule format that never includes sugar.
- Has undergone third-party safety testing, ingredient purity testing, made with traceable ingredients, and is shelf stable.
DOCTOR DEVELOPED
SUGAR FREE
NON-GMO
NO DYES
VEGAN
GLUTEN FREE
How To Use
How To Use
- Take 1 capsule daily, preferably with a meal.
- No refrigeration required!
- Consult your healthcare provider before starting any supplement regimen.
Ingredients
Ingredients
- Bacillus subtilis DE111®, lactobacillus acidophilus, lactobacillus gasseri, lactobacillus salivarius, lactobacillus brevis, lactobacillus rhamnosus, lactobacillus casei, lactobacillus plantarum, lactobacillus paracasei
- Other Ingredients: Inulin, hydroxypropyl methylcellulose (HPMC) capsule, medium chain triglycerides
Proof
Proof
- 2 million+ bottles sold
- 7,000 5-star reviews
- 97% felt that consistent use of Good Girl Probiotics® helped support consistent vaginal balance and healthy pH levels**
- 99% of consumers would recommend this product to a friend**
- "Best for Body Balance" -Harper's Bazaar
- "2023 Wellness Brand of the Year" -WWD's The Beauty Inc. Awards
Expert Opinions
Expert Opinions
"Research tells us that our gut and our vagina communicate via their respective microbiomes. Good Girl Probiotics® are special because they target that gut-vagina connection to help support vaginal health. Plus, I love that it's a sugar-free capsule instead of a gummy!"*
Dr. Gabrielle Francis, DC, ND, LAC
Naturopathic Doctor
Zyla Botanics Advisor
"Probiotics are essential for helping your body maintain a healthy community of microorganisms. Good Girl Probiotics® has nine strains of bacteria specific to the vaginal microbiome studied to support overall vaginal health."*
Dr. Jodie Horton, MD, FACOG
Board Certified OB/GYN
Zyla Botanics Advisor
A blend of probiotics and nootropics to help support brain function, cognitive health, and help maintain a healthy mood and sense of calm.*
- Vegan, Gluten-Free & Dairy-Free
- Take 1 capsule daily with or without food




WHY WE MADE GOOD GIRL PROBIOTICS®
In 2016, we couldn't find a supplement to support balanced vaginal pH anywhere.
So, we worked with our team of doctors to create an innovative, a 9- strain probiotic that helps support overall vaginal health via the gut-vagina microbiome connection.*
Today, it's one of our best sellers.
What we're made of
Good Girl Probiotics® is made with clinically studied ingredients that have been carefully selected by our team of doctors to support at the microbiome level.*
-
Bacillus subtilis DE111®
Clinically studied bacterial strain for enhanced product absorption.*
-
Lactobacillus acidophilus
Most-researched probiotic strain for maintaining a healthy vaginal balance.*
-
Lactobacillus plantarum
A lactic acid producer that helps support pH levels.*
-
Lactobacillus rhamnosus
Clinically shown to be able to interfere with growth of Candida yeast.*
-
Lactobacillus gasseri
Supports vaginal health by promoting balanced levels of good bacteria and fungi.*
What we never include
Our supplements are made without these all-too-common ingredients because we believe they belong nowhere near your wellness routine.
Collapsible content
SUGAR (REAL OR ARTIFICIAL)
We don't believe sugar supports your well-being, so we never include it in our supplements. You deserve real solutions you can trust for your body, not candy masked as wellness.
TAPIOCA SYRUP OR CORN SYRUP
We don't believe syrups (sugar hiding as a different ingredient) support your wellness goals, so we don't include them in our supplements. Prioritize results over sweetness by skipping the candy and choosing our capsules.
ARTIFICIAL COLORS
FD+C dyes have no place in supplements (or food in general). Skip colorful, candy-like supplement formats and choose our capsules every time.
ARTIFICIAL FLAVORS
We firmly believe that artificial flavors do not contribute to well-being. That's why we do not include them in our products. Our supplements are made as capsules, not candy, because we believe you deserve real solutions you can trust for your body.
Good Girl Probiotics® vs. Them
Committed to clinical studies
You deserve solutions backed by clinical studies. We’re one of the few brands investing in formula-level research—see our results!


FAQs
How do I take Good Girl Probiotics®?
Take 1 capsule daily, preferably with a meal. You can take Good Girl Probiotics® at a time of day that works best for you.
What's changed in the updated formula?
We’re constantly iterating, innovating, and improving our product line-up to bring you the best and most effective formulas. Here’s what we’ve updated in this new formula:
- Now includes 9 probiotic strains. An additional clinically studied bacterial strain helps with enhanced product absorption.*
- Now 1 capsule per serving. All ingredients now fit in a single, more digestible capsule.
- Now 100% vegan. This was our most requested change by our customers! An upgraded, veggie-based capsule that’s inclusive of more diets.
What hasn't changed in this updated formula?
You’ll still get all of the benefits of our original Good Girl Probiotics® formula, just with a more effective delivery via one capsule instead of two:
- Maintain a balanced vaginal pH, urinary tract functions, and healthy levels of vaginal yeast and bacteria*
- Shelf stable formula that doesn’t require refrigeration
- Supports three key areas of the body: reproductive health organs, the gut, and the immune system*
What should I expect when taking this new formula? Will I feel different or have different results?
You shouldn’t expect to see or feel any noticeable difference with this formula, other than taking one less capsule a day. With the addition of a clinically added probiotic strain, Bacillus subtilis DE111®for enhanced absorption, you’ll get a better, more impactful delivery of the other 8 probiotic strains so they’re most effective at doing what they do best - balancing your vaginal microbiome, bacteria, and pH levels.
Are there prebiotics in Good Girl Probiotics®?
Good Girl Probiotics® includes a prebiotic fiber, inulin, which supports the delivery of our formula by promoting the growth of beneficial bacteria. You can compare the function of a prebiotic to that of a fertilizer for a plant. While your plant may be fine without fertilizer, it grows much healthier with it! Similarly, a prebiotic works to support the probiotics (live bacteria) so that in return the probiotics can best support you!
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